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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKAA2 All Species: 13.64
Human Site: S534 Identified Species: 25
UniProt: P54646 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54646 NP_006243.2 552 62320 S534 S V S P R L G S H T M D F F E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086410 550 62775 P530 P V D L T P R P G S H T I E F
Dog Lupus familis XP_546691 722 81319 S704 S V P P R L G S H T M D F F E
Cat Felis silvestris
Mouse Mus musculus Q8BRK8 552 61988 S534 S A S P R L G S H T M D F F E
Rat Rattus norvegicus Q09137 552 62239 S534 S A S P R L G S H T M D F F E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506315 519 59478 P499 T A D L T S R P G S H T I E F
Chicken Gallus gallus Q9IA88 798 88848 S749 D T H L Y I S S N V S P V G T
Frog Xenopus laevis NP_001088426 560 64038 P540 N T D L V P R P G S H T I E F
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 G872 L K V P G L E G Y G L S Y G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623371 515 58559 H497 L P P Q T T G H H T M E F F E
Nematode Worm Caenorhab. elegans Q95ZQ4 626 70425 P598 D M S C D V T P P P S P G G A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38997 535 61163 P517 D L Q R V Q G P Q F L F L D L
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 D605 T V S N I S E D E M S T F S A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 76.4 73.8 N.A. 97.6 98.1 N.A. 71.1 27.3 75.3 22.3 N.A. N.A. 66.1 53.6 N.A.
Protein Similarity: 100 N.A. 86.7 75.2 N.A. 98.5 99 N.A. 81.1 42.6 85 32.6 N.A. N.A. 77.7 65.6 N.A.
P-Site Identity: 100 N.A. 6.6 93.3 N.A. 93.3 93.3 N.A. 0 6.6 0 13.3 N.A. N.A. 46.6 6.6 N.A.
P-Site Similarity: 100 N.A. 13.3 93.3 N.A. 93.3 93.3 N.A. 13.3 20 13.3 33.3 N.A. N.A. 53.3 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 44.9 33.1 N.A.
Protein Similarity: N.A. N.A. N.A. 62.3 50.2 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 0 0 0 0 0 0 0 0 0 0 0 0 16 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 24 0 24 0 8 0 0 8 0 0 0 31 0 8 0 % D
% Glu: 0 0 0 0 0 0 16 0 8 0 0 8 0 24 39 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 8 47 39 24 % F
% Gly: 0 0 0 0 8 0 47 8 24 8 0 0 8 24 8 % G
% His: 0 0 8 0 0 0 0 8 39 0 24 0 0 0 0 % H
% Ile: 0 0 0 0 8 8 0 0 0 0 0 0 24 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 16 8 0 31 0 39 0 0 0 0 16 0 8 0 8 % L
% Met: 0 8 0 0 0 0 0 0 0 8 39 0 0 0 0 % M
% Asn: 8 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 8 8 16 39 0 16 0 39 8 8 0 16 0 0 0 % P
% Gln: 0 0 8 8 0 8 0 0 8 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 31 0 24 0 0 0 0 0 0 0 0 % R
% Ser: 31 0 39 0 0 16 8 39 0 24 24 8 0 8 0 % S
% Thr: 16 16 0 0 24 8 8 0 0 39 0 31 0 0 8 % T
% Val: 0 31 8 0 16 8 0 0 0 8 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 8 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _